Engineering Approaches to Target Cancer and the Immune System | Aguilera Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/aguilera-lab/research/engineering-approaches-target-cancer-and-immune-system

With background in engineering biologic molecules to target the tumor microenvironment our lab is exploring opportunities to utilize molecular engineering techniques to develop immune active therapies. 

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource

https://labs.utsouthwestern.edu/sites/default/files/2023-07/Data%20Science%20Collaboration%20Agreement.pdf

Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science Collaboration Agreement SCCC-DSSR This agreement is between the DSSR user named below and the Director of SCCC-DSSR, Professor Jeon Lee.

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource

https://labs.utsouthwestern.edu/sites/default/files/2023-07/Data%20Science%20On%20Demand%20User%20Agreement_1.pdf

Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science On-Demand User Agreement SCCC-DSSR This agreement is between the DSSR client named below and the Director of SCCC-DSSR, Professor Jeon Lee.

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource

https://labs.utsouthwestern.edu/sites/default/files/2023-07/Data%20Science%20Fellowship%20Agreement.pdf

Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science Fellowship Agreement SCCC-DSSR This agreement is between the parties named below and the Director of SCCC-DSSR, Professor Jeon Lee.

Precursors of Type II Endometrial Cancer | Zheng Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/zheng-lab/research/precursors-type-ii-endometrial-cancer

Cell and Molecular Biology Clinical Psychology Genetics, Development and Disease Immunology Molecular Biophysics Molecular Microbiology Neuroscience Organic Chemistry Core Facilities > Precursors of Type II Endometrial Cancer P53 signature - latent precancer of type II endometrial cancer Based on our

Cancer Therapy Response Assessment using ASL | Madhuranthakam Lab | UT Southwestern, Dallas, Texas

https://labs.utsouthwestern.edu/madhuranthakam-lab/research/cancer-therapy-response-assessment-using-asl

Cancer Therapy Response Assessment using ASL | Madhuranthakam Lab | UT Southwestern, Dallas, Texas Skip to main content UT Southwestern Research Labs Madhuranthakam Lab × People Research Research sub-navigation Arterial Spin Labeled MRI Cancer Therapy Response Improved Fat/Water Separation Whole-Body

Polymeric micelle nanoparticles for photodynamic treatment of head and neck cancer cells

https://labs.utsouthwestern.edu/sites/default/files/2022-11/76_Cohen_Otolaryngology.pdf

In vitro cell culture using HSC-3 and HN-5 cancer cells was performed to test the photodynamic therapy efficacy of the micelles using confocal microscopy and method of transcriptional and translational (MTT) assay.

Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy

https://labs.utsouthwestern.edu/sites/default/files/2022-11/122_Luo_JCR_2019.pdf

The DNA of dying irradiated cancer cells are found in the cytoplasm of dendritic cells, which is responsible for the activation of the cGAS-STING-type I IFN pathway [9].

Nano-Immune-Engineering Approaches to Advance Cancer Immunotherapy: Lessons from Ultra-pH-Sensitive Nanoparticles

https://labs.utsouthwestern.edu/sites/default/files/2022-11/129_Li_ACR_2020-min.pdf

This Account highlights the development and implementation of ultra-pH-sensitive (UPS) nanoparticles in cancer immunotherapy with an emphasis on nanoscale cooperativity.

Combined radiofrequency ablation and doxorubicin-eluting polymer implants for liver cancer treatment

https://labs.utsouthwestern.edu/sites/default/files/2022-11/52_Weinberg2_JBMR_2007.pdf

Doxorubicin was used in the implants because of its previously reported success in combination with RF ablation13,14 and clinical use in liver cancer therapy.24 The drug also has natural fluo- rescence, which allows for characterization of local drug distribution in tumor/liver tissues.